论文标题
在活性杆环境中的聚合物易位
Polymer translocation in an environment of active rods
论文作者
论文摘要
我们考虑柔性线性聚合物通过纳米孔进入{\ it trans}侧中活性杆的环境的易位过程的动力学。使用Langevin Dynamics模拟，我们发现杆促进{\ it trans}侧的易位，即使最初在{\ it cis}上比{\ it trans} side上的单体更多。易位聚合物的结构分析表明，在成功的易位事件的情况下，活性杆会诱导{\ it trans} - 侧链折叠结构。通过将单体的初始数量保持在{\ it cis} - 侧链固定上，我们将成功事件的状态图绘制为各种系统参数的杆数密度的函数。这揭示了杆的促进与低密度的拥挤之间的竞争，从而阻碍了更高密度的易位。
We consider the dynamics of a translocation process of a flexible linear polymer through a nanopore into an environment of active rods in the {\it trans} side. Using Langevin dynamics simulations we find that the rods facilitate translocation to the {\it trans} side even when there are initially more monomers on the {\it cis} than on the {\it trans} side. Structural analysis of the translocating polymer reveals that active rods induce a folded structure to the {\it trans}-side subchain in the case of successful translocation events. By keeping the initial number of monomers on the {\it cis}-side subchain fixed, we map out a state diagram for successful events as a function of the rod number density for a variety of system parameters. This reveals competition between facilitation by the rods at low densities and crowding that hinders translocation at higher densities.
