论文标题

从连续的医学数据中学习预测清单

Learning predictive checklists from continuous medical data

论文作者

Makhija, Yukti, De Brouwer, Edward, Krishnan, Rahul G.

论文摘要

清单虽然直到最近才在医疗领域引入,但由于其效率和出色的解释性,在日常临床实践中已变得非常流行。清单通常是由专业临床医生设计的,这些临床医生手动收集和分析可用证据。但是,可用的医疗数据数量的增加是需要部分自动化的清单设计。最近的工作通过从分类数据中学习预测清单朝着这个方向迈出了一步。在这项工作中,我们建议使用混合智能编程方法从连续的医疗数据中扩展这种方法,以适应学习清单。我们表明,这一扩展优于一系列可解释的机器学习基线,内容涉及重症监护临床轨迹的败血症。

Checklists, while being only recently introduced in the medical domain, have become highly popular in daily clinical practice due to their combined effectiveness and great interpretability. Checklists are usually designed by expert clinicians that manually collect and analyze available evidence. However, the increasing quantity of available medical data is calling for a partially automated checklist design. Recent works have taken a step in that direction by learning predictive checklists from categorical data. In this work, we propose to extend this approach to accomodate learning checklists from continuous medical data using mixed-integer programming approach. We show that this extension outperforms a range of explainable machine learning baselines on the prediction of sepsis from intensive care clinical trajectories.

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