论文标题
在金星生命命令宣教概念研究中,用流体屏幕对生物颗粒进行直接捕获,分离和可视化
Direct In-Situ Capture, Separation and Visualization of Biological Particles with Fluid-Screen in the Context of Venus Life Finder Mission Concept Study
论文作者
论文摘要
在维纳斯气氛中,化学不平衡和其他异常观察的证据激发了地球温带云中寻找生命的证据。为了找到维纳斯航空生物圈的迹象,需要专门的天体空间任务。金星生活发现者(VLF)任务包括独特的任务概念,并带有专门的工具来寻找可居住的指标,生物签名甚至生活本身。寻找生命的关键是生物潜力颗粒的直接捕获,浓度和可视化。在这里,我们介绍了流体屏幕(FS)技术的简短概述,这是介电性(DEP)微生物颗粒捕获,浓度和分离的最新进步。 FS能够根据粒子介电性能捕获和分离生化多样的颗粒,包括多细胞霉菌,真核细胞,不同种类的细菌甚至病毒。在这种简短的沟通中,我们讨论了在VLF任务的背景下可能实施流体屏幕,并强调了流体屏幕仪器的独特科学输出。 FS可以与其他高度复杂的仪器(例如自动荧光显微镜或激光解吸质谱仪)结合使用。我们讨论了可以对金星进行修改和测试后的流体屏幕构型。我们讨论了FS技术的独特科学输出,可以捕获其本地状态的生物颗粒,并将其固定在显微镜的焦平面上,以直接成像被捕获的材料。我们讨论了金星云中浓硫酸环境所提出的方法的挑战。虽然金星的云是一个特别具有挑战性的环境,但太阳系的其他物体,例如,存在液态水,可能特别适合用于流体屏幕应用。
Evidence of chemical disequilibria and other anomalous observations in the Venusian atmosphere motivate the search for life within the planet's temperate clouds. To find signs of a Venusian aerial biosphere, a dedicated astrobiological space mission is required. Venus Life Finder (VLF) missions encompass unique mission concepts with specialized instruments to search for habitability indicators, biosignatures and even life itself. A key in the search for life is direct capture, concentration and visualization of particles of biological potential. Here, we present a short overview of Fluid-Screen (FS) technology, a recent advancement in the dielectrophoretic (DEP) microbial particle capture, concentration and separation. FS is capable of capturing and separating biochemically diverse particles, including multicellular molds, eukaryotic cells, different species of bacteria and even viruses, based on particle dielectric properties. In this short communication, we discuss the possible implementation of Fluid-Screen in the context of the VLF missions, emphasizing the unique science output of the Fluid-Screen instrument. FS can be coupled with other highly sophisticated instruments such as an autofluorescence microscope or a laser desorption mass spectrometer. We discuss possible configurations of Fluid-Screen that upon modification and testing, could be adapted for Venus. We discuss the unique science output of the FS technology that can capture biological particles in their native state and hold them in the focal plane of the microscope for the direct imaging of the captured material. We discuss the challenges for the proposed method posed by the concentrated sulfuric acid environment of Venus' clouds. While Venus' clouds are a particularly challenging environment, other bodies of the solar system, e.g., with liquid water present, might be especially suitable for Fluid-Screen application.