论文标题
非平衡波动和耗散的非平衡性粘弹性生物种类的非平衡模型
Non-Markovian modeling of non-equilibrium fluctuations and dissipation in active viscoelastic biomatter
论文作者
论文摘要
基于将示踪剂和活性颗粒之间的弹性耦合融合的哈密顿量，我们为主动粘弹性生物因素的非平衡机械响应提供了广义的langevin模型。我们的模型说明了嵌入聚合物网络的幂律粘弹性响应以及活动和示踪剂颗粒之间的非平衡能量转移。我们对频率响应函数和位置自相关函数的分析表达式与有或没有ATP的红细胞和肌动菌素网络的实验数据非常吻合。拟合的有效活性颗粒温度，弹性常数和我们模型的有效摩擦系数允许直接的物理解释。
Based on a Hamiltonian that incorporates the elastic coupling between a tracer and active particles, we derive a generalized Langevin model for the non-equilibrium mechanical response of active viscoelastic biomatter. Our model accounts for the power-law viscoelastic response of the embedding polymeric network as well as for the non-equilibrium energy transfer between active and tracer particles. Our analytical expressions for the frequency-dependent response function and the positional autocorrelation function agree nicely with experimental data for red blood cells and actomyosin networks with and without ATP. The fitted effective active-particle temperature, elastic constants and effective friction coefficients of our model allow straightforward physical interpretation.
