论文标题

快照CEST ++:下一个快速全脑APTW成像的快照CEST在3T

snapshot CEST++ : the next snapshot CEST for fast whole-brain APTw imaging at 3T

论文作者

Liebig, Patrick, Sedykh, Maria, Herz, Kai, Fabian, Moritz S., Mennecke, Angelika, Weinmüller, Simon, Schmidt, Manuel, Dörfler, Arnd, Zaiss, Moritz

论文摘要

CEST遇到了两个主要问题,长期以来的获取时间或限制的覆盖范围以及不一致的协议设置。在本文中,我们提供有关如何通过CEST优化协议设置的建议,并为APT CEST提供一个设置。为了增加覆盖范围,同时保持采集时间不变,我们建议使用空间时间压缩感测方法。最后,通过完全集成的在线重建,可以在不到2分钟的时间内获取1.8毫米各向同性的整个大脑APT CEST地图。这将为CEST的进一步临床使用铺平道路。

CEST suffers from two main problems long acquisitin times or restricted coverage as well as incoherent protocol settings. In this paper we give suggestions on how to optimise your protocol settings fro CEST and present one setting for APT CEST. To increase the coverage while keeping the acquisition time constant we suggest using a spatial temporal Compressed Sensing approach. Finally, 1.8mm isotropic whole brain APT CEST maps can be acquired in a little bit less than 2min with a fully integrated online reconstruction. This will pave the way to an even further clinical use of CEST.

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