论文标题

联合的多器官分割具有不一致的标签

Federated Multi-organ Segmentation with Inconsistent Labels

论文作者

Xu, Xuanang, Deng, Hannah H., Gateno, Jaime, Yan, Pingkun

论文摘要

联合学习是一种新兴的范式,允许大规模分散学习,而无需在不同的数据所有者中共享数据,这有助于解决医学图像分析中数据隐私的关注。但是,通过现有方法对客户的标签一致性的需求在很大程度上缩小了其应用程序范围。实际上,每个临床部位只能以部分或没有与其他站点重叠的某些感兴趣的器官注释某些感兴趣的器官。将这种部分标记的数据纳入统一联邦是一个未开发的问题,具有临床意义和紧迫性。这项工作通过使用一种新型联合的多层U-NET(FED-MENU)方法来应对挑战,以进行多器官分割。在我们的方法中,提出了一个多编码的U-NET(菜单网络),以通过不同的编码子网络提取器官特异性功能。每个子网络都可以看作是特定风琴的专家,并为该客户培训。此外,为了鼓励不同子网络提取的特定器官特定功能提供信息和独特的功能,我们通过设计辅助通用解码器(AGD)来对菜单网的培训进行正常训练。对六个公共腹部CT数据集进行的广泛实验表明,我们的FED-MENU方法可以使用具有优越性能的部分标记的数据集有效地获得联合学习模型,而不是由局部或集中学习方法培训的其他模型。源代码可在https://github.com/dial-rpi/fed-menu上公开获取。

Federated learning is an emerging paradigm allowing large-scale decentralized learning without sharing data across different data owners, which helps address the concern of data privacy in medical image analysis. However, the requirement for label consistency across clients by the existing methods largely narrows its application scope. In practice, each clinical site may only annotate certain organs of interest with partial or no overlap with other sites. Incorporating such partially labeled data into a unified federation is an unexplored problem with clinical significance and urgency. This work tackles the challenge by using a novel federated multi-encoding U-Net (Fed-MENU) method for multi-organ segmentation. In our method, a multi-encoding U-Net (MENU-Net) is proposed to extract organ-specific features through different encoding sub-networks. Each sub-network can be seen as an expert of a specific organ and trained for that client. Moreover, to encourage the organ-specific features extracted by different sub-networks to be informative and distinctive, we regularize the training of the MENU-Net by designing an auxiliary generic decoder (AGD). Extensive experiments on six public abdominal CT datasets show that our Fed-MENU method can effectively obtain a federated learning model using the partially labeled datasets with superior performance to other models trained by either localized or centralized learning methods. Source code is publicly available at https://github.com/DIAL-RPI/Fed-MENU.

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