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Training models dedicated to semantic segmentation requires a large amount of pixel-wise annotated data. Due to their costly nature, these annotations might not be available for the task at hand. To alleviate this problem, unsupervised domain adaptation approaches aim at aligning the feature distributions between the labeled source and the unlabeled target data. While these strategies lead to noticeable improvements, their effectiveness remains limited. To guide the domain adaptation task more efficiently, previous works attempted to include human interactions in this process under the form of sparse single-pixel annotations in the target data. In this work, we propose a new domain adaptation framework for semantic segmentation with annotated points via active selection. First, we conduct an unsupervised domain adaptation of the model; from this adaptation, we use an entropy-based uncertainty measurement for target points selection. Finally, to minimize the domain gap, we propose a domain adaptation framework utilizing these target points annotated by human annotators. Experimental results on benchmark datasets show the effectiveness of our methods against existing unsupervised domain adaptation approaches. The propose pipeline is generic and can be included as an extra module to existing domain adaptation strategies.