论文标题
用微流体芯片作为液体测量的传感器，用微流体芯片作为液体的石英窃窃私语模式谐振器
Quartz Whispering-Gallery-Mode Resonator with Microfluidic Chip as Sensor for Permittivity Measurement of Liquids
论文作者
论文摘要
生物溶液的研究需要高测量的精度，检测物质浓度较低的较低变化的能力以及正在测试的少量液体。一种基于高质量的小因素窃窃私语模式谐振器，具有微流体芯片的微波复合介电常数测量技术可以高精度地研究少量的介电液体。基于蓝宝石谐振器的现有技术不能为低分子量的物质提供低浓度检测极限。在这里，我们提出了一种基于石英介质谐振器的高级技术。发现水溶液中葡萄糖获得的检测极限对于石英谐振细胞的数量级比基于蓝宝石谐振剂的测量池低约一个数量级。极限大约或低于人类血液中葡萄糖的浓度。这一事实意味着该技术可以用作微波范围内生物溶液研究的传感器。使用已发达的传感器成功地在KA频带中对葡萄糖，乳脂蛋白和牛血清白蛋白进行了研究。
Studies of biological solutions require high measurement accuracy, the ability to detect low changes in substance concentration, and small amounts of the liquid under test. A microwave complex permittivity measurement technique based on a high-quality-factor whispering-gallery-mode resonator with a microfluidic chip allows small amounts of dielectric liquids to be investigated with high accuracy. An existing technique based on a sapphire resonator does not provide for a low-concentration detection limit for substances with low molecular weight. Here, we present an advanced technique based on a quartz dielectric resonator. The detection limit obtained for glucose in water solution was found to be about one order of magnitude lower for the quartz resonator cell than for the sapphire-resonator-based measurement cell. The limit is about or lower than the concentration of glucose in human blood. This fact means that the technique can be used as the sensor for investigations of biological solutions in the microwave range. A study of glucose, lactalbumin, and bovine serum albumin was successfully performed in the Ka -band using the developed sensor.
