论文标题
基于高空间选择性和纳米沃顿力的微粒操纵的超高频率涡流镊子
Ultra-high frequency vortex-based tweezers for microparticles manipulation with high spatial selectivity and nanoNewton forces
论文作者
论文摘要
基于聚焦的声学涡旋的声学镊子为体外和体内远程操作对微米对象的体外和体内远程操作打开了一些巨大的观点，并具有结合的选择性和与任何其他无接触式操纵技术相关的选择性。然而，超高频率声学涡旋的合成精确地微米仍然是一个重大挑战。在本文中，基于螺旋形的互音传感器，使用活性全息源来实现250 MHz声学涡流的合成。结果表明，这种超高的频率涡流使能够在具有高空间选择性和纳米沃顿力的标准显微镜环境中捕获和定位单个颗粒。这项工作打开了探索以前无法访问的力量范围的声学光谱的观点。
Acoustical tweezers based on focused acoustical vortices open some tremendous perspectives for the in vitro and in vivo remote manipulation of millimetric down to micrometric objects, with combined selectivity and applied forces out of reach with any other contactless manipulation technique. Yet, the synthesis of ultra-high frequency acoustical vortices to manipulate precisely micrometric objects remains a major challenge. In this paper, the synthesis of a 250 MHz acoustical vortex is achieved with an active holographic source based on spiraling interdigitated transducers. It is shown that this ultra-high frequency vortex enables to trap and position individual particles in a standard microscopy environment with high spatial selectivity and nanoNewton forces. This work opens perspectives to explore acoustic force spectroscopy in some force ranges that were not accessible before.
