学术文献库

Contacts' temporal ordering and dynamics are crucial for understanding the transmission of infectious diseases. We introduce an interaction-driven model of an airborne disease over contact networks. We demonstrate our interaction-driven contagion model, instantiated for COVID-19, over history-maintaining random temporal networks and real-world contacts. We use it to evaluate temporal, spatiotemporal, and spatial social distancing policies. We find that a spatial distancing policy is mainly beneficial at the early stages of a disease. We then continue to evaluate temporal social distancing, that is, timeline dilation that maintains the activity potential. We expand our model to consider the exposure to viral load, which we correlate with meetings' duration. Using real-life contact data, we demonstrate the beneficial effect of timeline dilation on overall infection rates. Our results demonstrate that given the same transmission level, there is a decrease in the disease's infection rate and overall prevalence under timeline dilation conditions. We further show that slow-spreading pathogens (i.e., require more prolonged exposure to infect) spread roughly at the same rate as fast-spreading ones in highly active communities. This is surprising since slower pathogens follow paths that include longer meetings, while faster pathogens can potentially follow paths that include shorter meetings, which are more common. Our results demonstrate that the temporal dynamics of a community have a more significant effect on the spread of the disease than the characteristics of the spreading processes.