学术文献库

CT images have been used to generate radiation therapy treatment plans for more than two decades. Dual-energy CT (DECT) has shown high accuracy in estimating electronic density or proton stopping-power maps used in treatment planning. However, the presence of metal implants introduces severe streaking artifacts in the reconstructed images, affecting the diagnostic accuracy and treatment performance. In order to reduce the metal artifacts in DECT, we introduce a metal-artifact reduction scheme for iterative DECT algorithms. An estimate is substituted for the corrupt data in each iteration. We utilize normalized metal-artifact reduction (NMAR) composed with image-domain decomposition to initialize the algorithm and speed up the convergence. A fully 3D joint statistical DECT algorithm, dual-energy alternating minimization (DEAM), with the proposed scheme is tested on experimental and clinical helical data acquired on a Philips Brilliance Big Bore scanner. We compared DEAM with the proposed method to the original DEAM and vendor reconstructions with and without metal-artifact reduction for orthopedic implants (O-MAR). The visualization and quantitative analysis show that DEAM with the proposed method has the best performance in reducing streaking artifacts caused by metallic objects.