论文标题
通过有机水溶剂混合物中的氨基酸速度颠簸调节[2]轮济中的大环梭子。
Regulation of macrocycle shuttling in [2]rotaxanes by amino-acid speed bumps in organic-aqueous solvent mixtures
论文作者
论文摘要
已经开发了一系列同源的两站[2]旋转烷，其中掺入分子螺纹中的氨基酸单元。退化[2]轮济表现出与与氨基酸侧链相关的空间因子相关的两个富马型站之间的氨基酸特异性穿梭率，如可变温度1H NMR光谱和交换光谱光谱学（EXSY）所证明的那样。这允许调整超过4个数量级的大环班车速率，这进一步具有相对较小的溶剂依赖性。
A homologous series of two-station [2]rotaxanes incorporating amino-acid units in the molecular thread has been developed. The degenerate [2]rotaxanes exhibit amino-acid specific shuttling rates between two fumaric stations related to the steric factor associated to the amino-acid side chain, as demonstrated by variable-temperature 1H NMR spectroscopy and exchange spectroscopy (EXSY). This allows tuning of the macrocycle shuttling rate over 4 orders of magnitude, which further has a relatively small solvent dependency.
