论文标题
具有可编程声学延迟线的低成本光声断层扫描系统
Low-Cost Optoacoustic Tomography System with Programmable Acoustic Delay-Line
论文作者
论文摘要
光声断层扫描(PAT)是一种用于生物医学成像的新兴技术,结合了高光学对比度和声学渗透的优势。在PAT系统中,优先检测到更多的光声(PA)信号从全视野中检测到以更高的保真度重建PA图像。但是,对基于阵列的PAT系统的基于单渠道扫描的PAT系统或更高的数据获取成本(DAQ)模块更高的PA信号检测的需求会导致更多的时间消耗。为了解决这个问题,我们提出了一个可编程的声学延迟线模块,以降低DAQ成本并加速PAT系统的成像速度。该模块基于声信号和电信号之间的双向转换,包括之间的超声传输以提供足够的时间延迟。声学延迟线模块可为每个通道实现数十或数百个微秒的延迟,并由可编程控制单元控制。在这项工作中,它可以将PA信号的四个输入合并到一个输出信号中,该信号可以在DAQ之后将其回收到数字域中的原始四个PA信号中。嵌入在琼脂幻影中的铅笔铅的成像实验是由配备有可编程的声学延迟线模块的PAT系统进行的,这表明其在生物医学成像系统中的可行性。
Photoacoustic tomography (PAT) is an emerging technology for biomedical imaging that combines the superiorities of high optical contrast and acoustic penetration. In the PAT system, more photoacoustic (PA) signals are preferred to be detected from full field of view to reconstruct PA images with higher fidelity. However, the requirement for more PA signals detection leads to more time consumption for single-channel scanning based PAT system, or higher cost of data acquisition (DAQ) module for an array-based PAT system. To address this issue, we proposed a programmable acoustic delay line module to reduce DAQ cost and accelerate imaging speed for PAT system. The module is based on bidirectional conversion between acoustic signals and electrical signals, including ultrasound transmission in between to provide sufficient time delay. The acoustic delay line module achieves tens or hundreds of microseconds delay for each channel, and is controlled by a programmable control unit. In this work, it achieves to merge four inputs of PA signals into one output signal, which can be recovered into original four PA signals in the digital domain after DAQ. The imaging experiments of pencil leads embedded in agar phantom is conducted by the PAT system equipped with the proposed programmable acoustic delay-line module, which demonstrated its feasibility in biomedical imaging system.