论文标题
电力法中浓度鲁棒性的计算方法shinar-feinberg类型的动力学系统
A computational approach to concentration robustness in power law kinetic systems of Shinar-Feinberg type
论文作者
论文摘要
最近有理论结果为在幂律动力学(PLK)系统中表现出绝对浓度鲁棒性(ACR)的物种提供了足够的条件。这样的结果之一涉及通过将ACR作为本地特性的较低缺陷子网视为较低的缺陷子网络来检测ACR。反过来,这个“较小”子网作为较大的ACR填充网络的“构建块”。在这里,以该定理为基础,我们构建了一种系统地检查PLK系统中ACR的算法。通过稍微修改算法,我们还提供了一个程序,该程序可以识别PLK系统中平衡浓度鲁棒性(BCR),浓度鲁棒性较弱。
There have been recent theoretic results that provide sufficient conditions for the existence of a species displaying absolute concentration robustness (ACR) in a power law kinetic (PLK) system. One such result involves the detection of ACR among networks of high deficiency by considering a lower deficiency subnetwork with ACR as a local property. In turn, this "smaller" subnetwork serves as a "building block" for the larger ACR-possessing network. Here, with this theorem as foundation, we construct an algorithm that systematically checks ACR in a PLK system. By slightly modifying the algorithm, we also provide a procedure that identifies balanced concentration robustness (BCR), a weaker form of concentration robustness than ACR, in a PLK system.