论文标题
超霉素闪烁剂量测量平台的比较视频和剂量计的多点应用程序
Comparative optic and dosimetric characterization of the HYPERSCINT scintillation dosimetry research platform for multipoint applications
论文作者
论文摘要
这项研究介绍了Hyperscint研究平台，这是第一个通过高光谱方法进行多点剂量计的商用闪烁剂量测定平台。通过与另一种市售溶液The Ocean Optics QE65PRO光谱仪进行比较，研究了系统的光学和剂量学性能。光学表征是通过测量信号的线性作为整合时间，光子检测效率和两个系统的光谱分辨率的函数来完成的。然后，用三点塑料闪烁体检测器（MPSD）评估剂量表性能，以信号与噪声比（SNR）和信号比率（SBR）（SBR）（SBR）（SBR）（SBR）评估。随后将后者与文献中发现的exradin W1（单点塑料闪烁体检测器）进行了比较。最后，使用Hyperscint平台实现了各种光束测量值，以评估其执行临床光子束剂量法的能力。发现两个系统在信号的线性方面都是可比的，这是强度的函数。尽管QE65Pro具有较高的光谱分辨率，但高血压的检测效率高达1000次。剂量测量表明，后者还提供了更好的SNR和SBR，甚至超过了Exradin W1单点PSD的SNR。尽管使用与MPSD耦合的HypersCint平台准确测量了从1 CGY到600 CGY的剂量在预测剂量的2.1％之内，但海洋光谱仪显示出在50CGY以下的差异高达86％。同样，使用HyperScint平台在预测剂量的2.3％内准确测量了梁曲线的最大区域的深度剂量，全宽度，并且平均差异分别为0.5％，1.6％和0.6％。
This study introduces the HYPERSCINT research platform, the first commercially available scintillation dosimetry platform capable of multi-point dosimetry through the hyperspectral approach. Optic and dosimetric performances of the system were investigated through comparison with another commercially available solution, the Ocean Optics QE65Pro spectrometer. The optical characterization was accomplished by measuring the linearity of the signal as a function of integration time, photon detection efficiency and spectral resolution for both systems. Dosimetric performances were then evaluated with a 3-point plastic scintillator detector (mPSD) in terms of signal to noise ratio (SNR) and signal to background ratio (SBR) associated with each scintillator. The latter were subsequently compared with those found in the literature for the Exradin W1, a single-point plastic scintillator detector. Finally, various beam measurements were realized with the HYPERSCINT platform to evaluate its ability to perform clinical photon beam dosimetry. Both systems were found to be comparable in terms of linearity of the signal as a function of the intensity. Although the QE65Pro possesses a higher spectral resolution, the detection efficency of the HYPERSCINT is up to 1000 time greater. Dosimetric measurements shows that the latter also offers a better SNR and SBR, surpassing even the SNR of the Exradin W1 single-point PSD. While the doses ranging from 1 cGy to 600 cGy were accurately measured within 2.1% of the predicted dose using the HYPERSCINT platform coupled to the mPSD, the Ocean optics spectrometer shows discrepencies up to 86% under 50cGy. Similarly, depth dose, full width at half maximum region of the beam profile and output factors were all accurately measured within 2.3% of the predicted dose using the HYPERSCINT platform and exhibit an average difference of 0.5%, 1.6% and 0.6%, respectively.
