论文标题
增强的3D心肌应变估计来自多视图2D CMR成像
Enhanced 3D Myocardial Strain Estimation from Multi-View 2D CMR Imaging
论文作者
论文摘要
在本文中,我们提出了一个增强的3D心肌应变估计过程,该过程结合了来自单个成像方式的多个方向的互补位移信息(未标记的CMR SSFP图像)。为了估算左心室的心肌菌株,我们通过在商业软件(段,MEDVISO)中实现的2D非刚性注册算法注册了短轴,四腔和两腔视图。然后,我们为运动的三个正交方向创建了一系列插值函数,并使用它们将患者特异性左心室的四面体网格表示变形。此外,我们通过引入基于沿长轴位移的加权方案来纠正高估位移。该程序在包含16位健康志愿者的CMR SSFP图像的Stacom 2011数据集上进行了评估。与报道的挑战结果相比,我们在估计三种应变成分(径向,圆周,纵向)方面的准确性提高了,对于感兴趣的成像方式(SSFP)。我们的峰值应变估计值也可以显着接近于使用片段应变分析模块的文献中较大队列的研究和我们自己的地面真实测量的研究。我们提出的过程提供了一种相对快速,简单的方法来改善2D跟踪结果,并具有从其他图像模式中变形重建的网格模型或使用内置CMR网格重建过程的增加灵活性。我们提出的方案使用最常见的成像方式,通常在临床环境中给予变形的左心室特异性模型,而无需其他或专业的成像方案。
In this paper, we propose an enhanced 3D myocardial strain estimation procedure, which combines complementary displacement information from multiple orientations of a single imaging modality (untagged CMR SSFP images). To estimate myocardial strain across the left ventricle, we register the sets of short-axis, four-chamber and two-chamber views via a 2D non-rigid registration algorithm implemented in a commercial software (Segment, Medviso). We then create a series of interpolating functions for the three orthogonal directions of motion and use them to deform a tetrahedral mesh representation of a patient-specific left ventricle. Additionally, we correct for overestimation of displacement by introducing a weighting scheme that is based on displacement along the long axis. The procedure was evaluated on the STACOM 2011 dataset containing CMR SSFP images for 16 healthy volunteers. We show increased accuracy in estimating the three strain components (radial, circumferential, longitudinal) compared to reported results in the challenge, for the imaging modality of interest (SSFP). Our peak strain estimates are also significantly closer to reported measurements from studies of a larger cohort in the literature and our own ground truth measurements using Segment Strain Analysis Module. Our proposed procedure provides a relatively fast and simple method to improve 2D tracking results, with the added flexibility in either deforming a reconstructed mesh model from other image modalities or using the built-in CMR mesh reconstruction procedure. Our, proposed scheme presents a deforming patient-specific model of the left ventricle, using the commonest imaging modality , routinely administered in clinical settings, without requiring additional or specialized imaging protocols.