论文标题

反应扩散网络上有效的非局部核

Effective nonlocal kernels on Reaction-diffusion networks

论文作者

Ei, Shin-Ichiro, Ishii, Hiroshi, Kondo, Shigeru, Miura, Takashi, Tanaka, Yoshitaro

论文摘要

提出了一种从任何给定的反应扩散网络中得出基本积分内核的新方法。任何描述代谢物或任意许多因素的信号的网络都可以降低为一个称为“有效方程式”的单个差异方程的单个或更简单的系统系统,包括卷积类型中减少的积分内核(称为“有效内核”)。作为一个典型的例子,墨西哥帽子形的内核是从两个组件激活剂抑制剂系统中得出的。还表明,具有与激活剂抑制剂系统完全不同的三个组件系统还原为墨西哥帽子形内核的有效方程式。这意味着两个不同的系统基本上具有相同的有效方程式,并且它们基本上表现出相同的空间和时间模式。因此,我们可以通过减少的有效核在统一概念中识别两个不同的系统。还给出了该方法的其他两个应用:对皮肤上的色素模式的应用(具有远距离相互作用的两个因素网络)和大脑视觉系统中的分化波(称为龙的波浪)(具有远距离相互作用的四个因素网络)。在应用程序中,我们观察到通过有效方程的数值模拟在现有模型中出现的相同的空间和时间模式的再现。

A new method to derive an essential integral kernel from any given reaction-diffusion network is proposed. Any network describing metabolites or signals with arbitrary many factors can be reduced to a single or a simpler system of integro-differential equations called "effective equation" including the reduced integral kernel (called "effective kernel" ) in the convolution type. As one typical example, the Mexican hat shaped kernel is theoretically derived from two component activator-inhibitor systems. It is also shown that a three component system with quite different appearance from activator-inhibitor systems is reduced to an effective equation with the Mexican hat shaped kernel. It means that the two different systems have essentially the same effective equations and that they exhibit essentially the same spatial and temporal patterns. Thus, we can identify two different systems with the understanding in unified concept through the reduced effective kernels. Other two applications of this method are also given: Applications to pigment patterns on skins (two factors network with long range interaction) and waves of differentiation (called proneural waves) in visual systems on brains (four factors network with long range interaction). In the applications, we observe the reproduction of the same spatial and temporal patterns as those appearing in pre-existing models through the numerical simulations of the effective equations.

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