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The characteristic feature of 5G is the diversity of its services for different user needs. However, the requirements for these services are competing in nature, which impresses the necessity of a coordinated and flexible network architecture. Although coordinated multipoint (CoMP) systems were primarily proposed to improve the cell edge performance in 4G, their collaborative nature can be leveraged to support the diverse requirements and enabling technologies of 5G and beyond networks. To this end, we propose generalization of CoMP to a proactive and efficient resource utilization framework capable of supporting different user requirements such as reliability, latency, throughput, and security while considering network constraints. This article elaborates on the multiple aspects, inputs, and outputs of the generalized CoMP (GCoMP) framework. Apart from user requirements, the GCoMP decision mechanism also considers the CoMP scenario and network architecture to decide upon outputs such as CoMP technique or appropriate coordinating clusters. To enable easier understanding of the concept, popular use cases, such as vehicle-to-everything (V2X) communication and eHealth, are studied. Additionally, interesting challenges and open areas in GCoMP are discussed.