论文标题
跨全球注意力图药物处方的内核网络预测
Cross-Global Attention Graph Kernel Network Prediction of Drug Prescription
论文作者
论文摘要
我们提出了一种端到端,可解释的深度学习结构,以学习预测慢性病药物处方结果的图表。这是通过使用电子健康记录的图形表示,通过支持向量机器目标的深度度量学习协作来实现。我们通过新颖的跨全球注意节点匹配患者图形,将预测模型作为二进制图分类问题,通过自适应学习的图形内核,同时在多个图上计算,而无需训练对或三胞胎生成。使用台湾国家健康保险研究数据库的结果表明,我们的方法在准确性和解释性方面都优于当前的开始模型。
We present an end-to-end, interpretable, deep-learning architecture to learn a graph kernel that predicts the outcome of chronic disease drug prescription. This is achieved through a deep metric learning collaborative with a Support Vector Machine objective using a graphical representation of Electronic Health Records. We formulate the predictive model as a binary graph classification problem with an adaptive learned graph kernel through novel cross-global attention node matching between patient graphs, simultaneously computing on multiple graphs without training pair or triplet generation. Results using the Taiwanese National Health Insurance Research Database demonstrate that our approach outperforms current start-of-the-art models both in terms of accuracy and interpretability.