论文标题

最小二乘有限元方法用于肝弦血流

Least Squares Finite Element Method for Hepatic Sinusoidal Blood Flow

论文作者

Bertrand, Fleurianne, Lambers, Lena, Ricken, Tim

论文摘要

复杂的生物系统的模拟,例如对器官的血流描述,需要大量的计算能力以及对器官生理学的详细描述。我们提出了一种新型的最小二乘离散方法,用于使用肝组织的多孔培养基方法模拟肝小叶中正弦血流。不同最小二乘项的缩放术会导致鲁棒算法,并且固有的误差估计器提供了有效的改进策略。

The simulation of complex biological systems such as the description of blood flow in organs requires a lot of computational power as well as a detailed description of the organ physiology. We present a novel Least-Squares discretization method for the simulation of sinusoidal blood flow in liver lobules using a porous medium approach for the liver tissue. The scaling of the different Least-Squares terms leads to a robust algorithm and the inherent error estimator provides an efficient refinement strategy.

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