论文标题

在COVID-19的角度,对呼吸液滴干燥和降水动力学的见解

Insights on drying and precipitation dynamics of respiratory droplets in the perspective of Covid-19

论文作者

Kabi, Prasenjit, Saha, Abhishek, Chaudhuri, Swetaprovo, Basu, Saptarshi

论文摘要

我们分离了替代粘膜溶液液的纳米胶体液滴,以获得对19009年大流行期间空气传播核的感染性的基本见解。用盐水溶液在声音悬浮剂中的病毒载荷载量的盐水溶液进行。我们试图模仿这种空气粘膜滴滴的干燥,流动和降水动力学。通过与健康受试者的实际样品进行的类似实验,对替代流体的观察结果得到了验证。关于最终的晶体尺寸,出现了独特的特征。对于不同尺寸和环境条件的初始液滴直径的20-30%始终是20-30%。悬浮的液滴中保存的沉淀物表明,总病毒体群体中有15%仍分散在空气脱落的空气传播核的外表面。如果呼吸液滴(较大的初始尺寸)放在表面上,然后在无柄模式下蒸发,则该部分将增加到〜90%。

We isolate a nano-colloidal droplet of surrogate mucosalivary fluid to gain fundamental insights into the infectivity of air borne nuclei during the Covid-19 pandemic. Evaporation experiments are performed with salt-water solutions seeded with a viral load of inactive nanoparticles in an acoustic levitator. We seek to emulate the drying, flow and precipitation dynamics of such air borne mucosalivary droplets. Observations with the surrogate fluid are validated by similar experiments with actual samples from a healthy subject. A unique feature emerges with regards to the final crystallite dimension; it is always 20-30% of the initial droplet diameter for different sizes and ambient conditions. The preserved precipitates from levitated droplets show that 15% of the total virion population remain dispersed on the outer surface of air-desiccated air borne nuclei. This fraction increases to ~90% if the respiratory droplets (of larger initial size) settle on a surface and then evaporate in the sessile mode.

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