论文标题

钻石量子温度计的光学检测到的磁共振变化的实时估计

Real-time estimation of the optically detected magnetic resonance shift in diamond quantum thermometry

论文作者

Fujiwara, Masazumi, Dohms, Alexander, Suto, Ken, Nishimura, Yushi, Oshimi, Keisuke, Teki, Yoshio, Cai, Kai, Benson, Oliver, Shikano, Yutaka

论文摘要

我们研究了纳米座(NDS)中氮化(ND)中心的光学检测到的磁共振(ODMR)的频移(ODMR)的实时估计方案。有效地将多点ODMR测量和ND颗粒跟踪整合到荧光显微镜中,最近显示了对活动物内部温度的稳定监测。我们详细分析了多点ODMR测量技术(3-,4-和6分方法),并量化了测量伪像的量,这是由于来自实验硬件和ODMR光谱形状的工具误差得出的几个系统误差。我们提出了一种实用方法来最大程度地减少这些因素的影响,从而可以在动态热事件中测量单个ND的准确温度。我们还讨论了噪声过滤器,数据估计协议的集成以及可能在实时温度估计中进一步发展的伪影。本研究提供了量子钻石温度计的技术细节,并讨论了可能影响生物应用温度估计的因素。

We investigate the real-time estimation protocols for the frequency shift of optically detected magnetic resonance (ODMR) of nitrogen-vacancy (NV) centers in nanodiamonds (NDs). Efficiently integrating multipoint ODMR measurements and ND particle tracking into fluorescence microscopy has recently demonstrated stable monitoring of the temperature inside living animals. We analyze the multipoint ODMR measurement techniques (3-, 4-, and 6-point methods) in detail and quantify the amount of measurement artifact owing to several systematic errors derived from instrumental errors of experimental hardware and ODMR spectral shape. We propose a practical approach to minimize the effect of these factors, which allows for measuring accurate temperatures of single NDs during dynamic thermal events. We also discuss integration of noise filters, data estimation protocols, and possible artifacts for further developments in real-time temperature estimation. The present study provides technical details of quantum diamond thermometry and discusses factors that may affect the temperature estimation in biological applications.

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