论文标题
不可能从TKF91模型下的序列长度进行一致的距离估计
Impossibility of consistent distance estimation from sequence lengths under the TKF91 model
论文作者
论文摘要
我们考虑了在系统发育中插入,缺失和取代的序列演变模型下距离估计的问题。在预期序列长度趋于无穷大的渐近状态下,我们表明,单独的序列长度不可能一致的距离估计。更正式的是,我们确定在不同距离处的序列长对分布无法通过概率为一个。
We consider the problem of distance estimation under the TKF91 model of sequence evolution by insertions, deletions and substitutions on a phylogeny. In an asymptotic regime where the expected sequence lengths tend to infinity, we show that no consistent distance estimation is possible from sequence lengths alone. More formally, we establish that the distributions of pairs of sequence lengths at different distances cannot be distinguished with probability going to one.