论文标题
折射校正的基于射线的反转,用于乳房的三维超声断层扫描
Refraction-corrected ray-based inversion for three-dimensional ultrasound tomography of the breast
论文作者
论文摘要
超声断层扫描在过去十年中引起了兴趣的复兴,尤其是对于乳房成像,由于超声和计算硬件的改善。特别是,三维超声断层扫描是一种完全层状方法,其中要成像的介质被超声传感器包围,已经变得可行。在本文中,提出了对半球探测器阵列的3D大规模弯曲射线超声断层扫描的鲁棒框架的全面推导和研究。得出了两种射线追踪方法。更重要的是,将发射器和接收器之间的射线联系起来的问题,由于射线轨迹的自由度高,这在3D中构成挑战,这既被分析为最小化又是一个根系问题。射线链接问题是针对凸检测表面的参数化,并且制定并证明了三种稳健,准确,有效的射线链接算法。为了稳定这些方法,提出了新型的自适应平滑方法,以控制更新矩阵的调理以确保准确的链接。估计声速的非线性UST问题是一系列线性的子问题,每个问题都使用上述算法和最陡峭的下降方案解决。证明了整个成像算法在使用全波声模型和解剖学乳腺模板模拟的现实数据上具有鲁棒性和准确性,并且由于误差的误差而包含了带有测量数据的飞行时间。该方法可以用来提供低艺术品,定量准确的3D音速图。除了自己有用外,此类3D音速图还可以用于初始化全波反倒置方法,也可以用作光声断层扫描重建的输入。
Ultrasound Tomography has seen a revival of interest in the past decade, especially for breast imaging, due to improvements in both ultrasound and computing hardware. In particular, three-dimensional ultrasound tomography, a fully tomographic method in which the medium to be imaged is surrounded by ultrasound transducers, has become feasible. In this paper, a comprehensive derivation and study of a robust framework for large-scale bent-ray ultrasound tomography in 3D for a hemispherical detector array is presented. Two ray-tracing approaches are derived and compared. More significantly, the problem of linking the rays between emitters and receivers, which is challenging in 3D due to the high number of degrees of freedom for the trajectory of rays, is analysed both as a minimisation and as a root-finding problem. The ray-linking problem is parameterised for a convex detection surface and three robust, accurate, and efficient ray-linking algorithms are formulated and demonstrated. To stabilise these methods, novel adaptive-smoothing approaches are proposed that control the conditioning of the update matrices to ensure accurate linking. The nonlinear UST problem of estimating the sound speed was recast as a series of linearised subproblems, each solved using the above algorithms and within a steepest descent scheme. The whole imaging algorithm was demonstrated to be robust and accurate on realistic data simulated using a full-wave acoustic model and an anatomical breast phantom, and incorporating the errors due to time-of-flight picking that would be present with measured data. This method can used to provide a low-artefact, quantitatively accurate, 3D sound speed maps. In addition to being useful in their own right, such 3D sound speed maps can be used to initialise full-wave inversion methods, or as an input to photoacoustic tomography reconstructions.