论文标题
病变后的功能补偿：预测部位和恢复程度
Functional compensation after lesions: Predicting site and extent of recovery
论文作者
论文摘要
在某些情况下，病变区域的功能可以由另一个区域补偿。但是，如果可以补偿其他区域的其他区域，则仍然是不可预测的。我们假设需要与损坏区域相同的功能进行类似的传入和传出连接。可以使用匹配索引在本地测量相似性，并通过非金属多维缩放（NMDS）来研究更全局的尺度。我们测试了两种措施如何预测小猫视觉皮层损失的补偿面积。对于此案例研究，连通性的全球比较结果是预测功能补偿的更好方法。在未来的研究中，病变和补偿区域之间相似性的程度可能是衡量可以成功恢复功能的程度。
In some cases, the function of a lesioned area can be compensated for by another area. However, it remains unpredictable if and by which other area a lesion can be compensated. We assume that similar incoming and outgoing connections are necessary to encode the same function as the damaged region. The similarity can be measured both locally using the matching index and looking at a more global scale by non-metric multidimensional scaling (NMDS). We tested how well both measures can predict the compensating area for the loss of the visual cortex in kittens. For this case study, the global comparison of connectivity turns out to be a better method for predicting functional compensation. In future studies, the extent of the similarity between the lesioned and compensating regions might be a measure of the extent to which function can be successfully recovered.
