论文标题
通过可重新配置的超光谱成像芯片获得的动态脑光谱
Dynamic brain spectrum acquired by a real-time ultra-spectral imaging chip with reconfigurable metasurfaces
论文作者
论文摘要
光谱成像为各种领域的铺平了铺平的方法，在生物医学研究中尤其是。但是，光谱成像主要取决于空间或时间扫描，无法同时实现高时间，空间和光谱分辨率。在这项研究中，我们证明了基于可重构跨面的硅实时超光谱成像芯片，其中包括155,216（356 $ \ times $ 436）图像自适应微光谱仪，具有超高的中心波长精度为0.04 nm和0.04 nm和频谱。它用于成像脑血流动力学，并获得了大鼠桶皮层中脱氧血红蛋白和氧降解性的动态光谱吸收特性，从而启发了体内研究的光谱和其他实时应用。
Spectral imaging paves way for various fields and particular in biomedical research. However, spectral imaging mainly depending on spatial or temporal scanning, cannot achieve high temporal, spatial and spectral resolution simultaneously. In this study, we demonstrated a silicon real-time ultra-spectral imaging chip based on reconfigurable metasurfaces, comprising of 155,216 (356$\times$436) image-adaptive micro-spectrometers with ultra-high center-wavelength accuracy of 0.04 nm and spectral resolution of 0.8 nm. It is employed for imaging brain hemodynamics, and the dynamic spectral absorption properties of deoxyhemoglobin and oxyhemoglobin in a rat barrel cortex were obtained, which enlighten the spectroscopy in vivo studies and other real-time applications.
