论文标题
呼吸道窦性心律不齐对心脏输出的数学和临床前研究
Mathematical and Preclinical Investigation of Respiratory Sinus Arrhythmia Effects on Cardiac Output
论文作者
论文摘要
呼吸窦性心律失常(RSA)是同步的心率变异性,尽管其功能意义尚不清楚。鼻窦心律失常的丧失可能表明心力衰竭或疾病;因此,知道它是如何工作并影响心脏呼吸系统的很大优势,尤其是通过提供数学模型。为此,使用Windkessel模型和心血管部分微分方程来基于与RSA相关的左心室弹性获得心脏输出。通过求解相应的方程式,可以提出一个新模型来预测RSA对心脏输出的影响。
Respiratory sinus arrhythmia (RSA) is heart rate variability in synchrony with respiration although its functional significance not clear. The loss of sinus arrhythmia may indicate underlying heart failure or disease; therefore, there would be a great advantage of knowing how it works and affects the cardio-respiratory system, especially by providing a mathematical model. To this end, Windkessel model and cardiovascular partial differential equations are used to obtain cardiac output based on the elasticity of left ventricle, which is related to RSA. By solving the corresponding equations, it would be possible to propose a new model to predict the RSA effects on cardiac output.