论文标题
Metasleeplearner:一项关于使用元学习的基于生物信号的睡眠阶段分类器快速适应新单个受试者的试点研究
MetaSleepLearner: A Pilot Study on Fast Adaptation of Bio-signals-Based Sleep Stage Classifier to New Individual Subject Using Meta-Learning
论文作者
论文摘要
识别基于生物信号的睡眠阶段需要熟练的临床医生的耗时和繁琐的劳动。已经引入了深度学习方法,以挑战自动睡眠阶段分类难题。但是,由于单个生物信号中许多方面的差异,因此在用自动系统替换临床医生时可能会带来困难,从而导致每个传入个体的模型表现不一致。因此,我们旨在探索使用一种新型方法,能够协助临床医生并减轻工作量的可行性。我们提出了基于模型不可知的元学习(MAML)的转移学习框架,标题为“ Metasleeplearner”,以将所获得的睡眠分期知识从大数据集转移到新的个体主题。证明该框架需要临床医生仅标记几个睡眠时期,并允许系统处理其余部分。层面相关性传播(LRP)也用于了解我们方法的学习过程。在所有获得的数据集中,与常规方法相比,Metasleeplearner的范围为5.4 \%至17.7 \%\%\%,两种方法平均值的统计差异。适应每个主题后模型解释的说明也证实了该表现是针对合理学习的。通过使用健康受试者和患者的记录进行微调,Metasleeplearner的表现优于常规方法。这是研究一种非惯性训练方法MAML的第一项工作,导致可能在睡眠阶段分类中进行人机合作,并减轻临床医生在仅通过几个时期标记睡眠阶段的负担,而不是整个记录。
Identifying bio-signals based-sleep stages requires time-consuming and tedious labor of skilled clinicians. Deep learning approaches have been introduced in order to challenge the automatic sleep stage classification conundrum. However, the difficulties can be posed in replacing the clinicians with the automatic system due to the differences in many aspects found in individual bio-signals, causing the inconsistency in the performance of the model on every incoming individual. Thus, we aim to explore the feasibility of using a novel approach, capable of assisting the clinicians and lessening the workload. We propose the transfer learning framework, entitled MetaSleepLearner, based on Model Agnostic Meta-Learning (MAML), in order to transfer the acquired sleep staging knowledge from a large dataset to new individual subjects. The framework was demonstrated to require the labelling of only a few sleep epochs by the clinicians and allow the remainder to be handled by the system. Layer-wise Relevance Propagation (LRP) was also applied to understand the learning course of our approach. In all acquired datasets, in comparison to the conventional approach, MetaSleepLearner achieved a range of 5.4\% to 17.7\% improvement with statistical difference in the mean of both approaches. The illustration of the model interpretation after the adaptation to each subject also confirmed that the performance was directed towards reasonable learning. MetaSleepLearner outperformed the conventional approaches as a result from the fine-tuning using the recordings of both healthy subjects and patients. This is the first work that investigated a non-conventional pre-training method, MAML, resulting in a possibility for human-machine collaboration in sleep stage classification and easing the burden of the clinicians in labelling the sleep stages through only several epochs rather than an entire recording.