论文标题
磁共振代谢成像的二氨基插值
Di-chromatic Interpolation of Magnetic Resonance Metabolic Imagery
论文作者
论文摘要
用超极化对比剂的磁共振成像可以提供代谢前所未有的\ textit {in-Vivo}测量，但产生的图像比质子解剖成像实现的图像低分辨率。为了在空间上定位代谢活性，必须将代谢图像插值到质子图像的大小。选择未知值的最常见方法仅依赖于原始未交互的图像的值。在这项工作中，我们提出了一种替代方法，该方法使用高分辨率质子图像提供其他空间结构。插值图像是凸优化算法的结果，该算法通过快速迭代收缩阈值算法（FISTA）求解。使用健康的人类志愿者的心脏和大脑数据，健康的猪心以及患有前列腺癌的人类的心脏和大脑数据显示了超极化丙酮酸，乳酸和碳酸氢盐的图像。
Magnetic resonance imaging with hyperpolarized contrast agents can provide unprecedented \textit{in-vivo} measurements of metabolism, but yields images that are lower resolution than that achieved with proton anatomical imaging. In order to spatially localize the metabolic activity, the metabolic image must be interpolated to the size of the proton image. The most common methods for choosing the unknown values rely exclusively on values of the original un-interpolated image. In this work, we present an alternative method that uses the higher-resolution proton image to provide additional spatial structure. The interpolated image is the result of a convex optimization algorithm which is solved with the Fast Iterative Shrinkage Threshold Algorithm (FISTA). Results are shown with images of hyperpolarized pyruvate, lactate, and bicarbonate using data of the heart and brain from healthy human volunteers, a healthy porcine heart, and a human with prostate cancer.
