论文标题
使用镜像双层结构的表面等离子体共振生物传感器的灵敏度增强灵敏度的数值分析
Numerical Analysis of Sensitivity Enhancement of Surface Plasmon Resonance Biosensors Using a Mirrored Bilayer Structure
论文作者
论文摘要
这里提出了一个镜像的双层结构，该结构融合了石墨烯和MOS2层以进行表面等离子体共振（SPR）生物传感，并通过数值评估其性能。从基本配置开始，使用石墨烯和MOS2层的结构逐渐开发出来以增强性能。反射率是绩效分析的主要参数。提出了基于菲涅尔方程的理论框架，并通过测量反射率与入射角，使用有限差分时间域（FDTD）技术从SPR角度的位移来计算灵敏度。我们的数值分析表明，使用所提出的方法，与基本的Kretschmann配置相比，可以提高灵敏度的4.2倍。值得注意的是，该结构为角度和波长询问提供了增强。此外，已经重复了各种结合配体对的模拟，并且已经观察到了一致的增强，这证明了结构的鲁棒性。因此，所提出的传感器架构显然可以显着提高灵敏度，这在各种实际应用中可能很重要。
A mirrored bilayer structure incorporating layers of Graphene and MoS2 is proposed here for Surface Plasmon Resonance (SPR) biosensing and its performance is evaluated numerically. Starting from the basic configuration, the structure with graphene and MoS2 layers is gradually developed for enhanced performance. Reflectance is the main considered parameter for performance analysis. A theoretical framework based on Fresnel's equations is presented and by measuring reflectance versus angle of incidence, sensitivity is calculated from the displacement of SPR angle using finite-difference time-domain (FDTD) technique. Our numerical analysis shows that using the proposed approach, about 4.2 times enhanced sensitivity can be achieved compared to the basic Kretschmann configuration. Notably, the structure provides an enhancement for both angular and wavelength interrogations. Furthermore, simulations have been repeated for various ligate-ligand pairs and consistent enhancement has been observed which proves the robustness of the structure. So, the proposed sensor architecture clearly provides pronounced improvement in sensitivity which can be significant in various practical applications.
