论文标题
在多尺度有序的胶原蛋白 - 二氧化碳bionanocomposites上的神经型细胞的分化
Differentiation of neural-type cells on multi-scale ordered collagen-silica bionanocomposites
论文作者
论文摘要
细胞对生物物理和生化信号的反应。我们开发了一种从经过修饰的胶原蛋白和二氧化硅颗粒与胶原蛋白相互作用和/或呈现层粘连蛋白表位（IKVAV）的复合细丝。这结合了脚手架和信号传导，并表明胶原蛋白组织的局部调整可以增强细胞分化。
Cells respond to biophysical and biochemical signals. We developed a composite filament from collagen and silica particles modified to interact with collagen and/or present a laminin epitope (IKVAV) crucial for cell-matrix adhesion and signal transduction. This combines scaffolding and signaling and shows that local tuning of collagen organization enhances cell differentiation.
