论文标题
达到缺血性中风中计算的侧支循环评分
Towards a Computed Collateral Circulation Score in Ischemic Stroke
论文作者
论文摘要
中风是全球残疾的第二大原因。为了最大程度地减少残疾，中风治疗的目的是保存血液供应减少但足以避免细胞死亡的地区的组织。血栓切除术已显示可提供快速有效的再灌注，并具有较高的再通速率。但是，由于血栓切除术的固有风险，应存在包括良好抵押循环的迹象。当前，评估侧支循环的方法有限。在这项工作中，我们提出了一种自动化技术，以根据4D血管造影图像中左右脑半球之间的平均强度中的差异来计算侧支循环评分。在这项初步研究中，我们分析了28名受试者的扫描：4个具有正常侧支循环的受试者，7个，中等，中间的10个，侧支循环较差（基于放射科医生得分），发现计算的分数与良好的分离和良好的分离和贫穷的组之间存在良好的相关性。这项工作显示了建立自动抵押循环评分的第一步。
Stroke is the second leading cause of disability worldwide. In order to minimize disability, the goal of stroke treatment is to preserve tissue in the area where blood supply is decreased but sufficient to stave off cell death. Thrombectomy has been shown to offer fast and efficient reperfusion with high recanalization rates. However, due to the inherent risks of thrombectomy, indications including evidence of good collateral circulation should be present. Currently, methods for evaluating collateral circulation are limited. In this work, we present an automated technique to compute a collateral circulation score based on differences seen in mean intensities between left and right cerebral hemispheres in 4D angiography images. In this preliminary study, we analyzed scans of 28 subjects: 4 with normal collateral circulation, 7 with good, 10 with intermediate, and 7 with poor collateral circulation, (based on radiologist score) and found a good correlation between the computed score and radiologist score (r2 = 0.71) and good separation between good and intermediate/poor groups. This work shows promise as the first step in building an automated collateral circulation score.
