论文标题

蒙特卡洛模拟生物组织中散射的圆形极化光,以使用自旋光发光发射二极管检测异常组织的检测技术

Monte Carlo simulation of scattered circularly polarized light in biological tissues for detection technique of abnormal tissues using spin-polarized light emitting diodes

论文作者

Nishizawa, Nozomi, Hamada, Atsushi, Takahashi, Kazumasa, Kuchimaru, Takahiro, Munekata, Hiro

论文摘要

生物组织散射的光的圆极化提供了有价值的信息,并被认为是诊断肿瘤组织的强大工具。我们建议使用配备有圆形极化发光二极管(Spin-LEDS)的内窥镜进行非染色,非侵入性和体内癌症诊断技术。我们使用现有的Monte Carlo方法研究了伪健康和癌组织中圆形极化光的散射过程。计算结果表明,散射在伪组织中的光的光的圆极化显示在广泛的检测角度上明显差异,而采样深度取决于这些检测角。内窥镜探针的结构包括自旋领导的探针,是根据计算结果设计的,同时提供了有关生物组织的结构和深度信息。

The circular polarization of light scattered by biological tissues provides valuable information and has been considered as a powerful tool for the diagnosis of tumor tissue. We propose a non-staining, non-invasive and in-vivo cancer diagnosis technique using an endoscope equipped with circularly polarized light-emitting diodes (spin-LEDs). We studied the scattering process of the circularly polarized light against cell nuclei in pseudo-healthy and cancerous tissues using the existing Monte Carlo method. The calculation results indicate that the resultant circular polarizations of light scattered in pseudo tissues shows clear difference in a wide range of detection angle, and the sampling depth depends on those detection angles. The structure of the endoscope probe comprising spin-LEDs is designed based on the calculation results, providing structural and depth information regarding biological tissues simultaneously.

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