论文标题

用于医学成像和光束表征的多光谱光子计数

Multispectral Photon-Counting for Medical Imaging and Beam Characterization

论文作者

Brücken, E., Bharthuar, S., Emzir, M., Golovleva, M., Gädda, A., Hostettler, R., Härkönen, J., Kirschenmann, S., Litichevskyi, V., Luukka, P., Martikainen, L., Naaranoja, T., Nincă, I., Ott, J., Petrow, H., Purisha, Z., Siiskonen, T., Särkkä, S., Tikkanen, J., Tuuva, T., Winkler, A.

论文摘要

我们介绍了开发用于医学成像的光子计数检测器的项目的当前状态。一个示例动机在生产用于硼中子捕获疗法的监测和剂量测定装置方面,目前尚未商业上可用。我们的方法结合了内部开发的基于洁牙池或厚硅的探测器,以及为CERN的粒子物理实验开发的读出芯片技术。在这里,我们描述了传感器的制造过程以及组装第一原型的处理步骤。这些原型使用当前的PSI46DIGV2.1-R读数芯片。还将讨论用于首次测量的随附的读取电子链。最终,我们提出了一种由我们开发的高级算法,该算法使用此类光子计数检测器以硼中子捕获疗法为重构。这项工作是在芬兰赫尔托大学,阿尔托大学,拉平兰特大学技术大学LUT与辐射与核安全局(Stuk)的赫尔辛基物理研究所的芬兰研究小组联盟内进行的。关键字:固态检测器,X射线检测器,伽马检测器,中子检测器,强子治疗仪器,医疗图像重建方法和算法。

We present the current status of our project of developing a photon counting detector for medical imaging. An example motivation lays in producing a monitoring and dosimetry device for boron neutron capture therapy, currently not commercially available. Our approach combines in-house developed detectors based on cadmium telluride or thick silicon with readout chip technology developed for particle physics experiments at CERN. Here we describe the manufacturing process of our sensors as well as the processing steps for the assembly of first prototypes. The prototypes use currently the PSI46digV2.1-r readout chip. The accompanying readout electronics chain that was used for first measurements will also be discussed. Finally we present an advanced algorithm developed by us for image reconstruction using such photon counting detectors with focus on boron neutron capture therapy. This work is conducted within a consortium of Finnish research groups from Helsinki Institute of Physics, Aalto University, Lappeenranta-Lahti University of Technology LUT and Radiation and Nuclear Safety Authority (STUK) under the RADDESS program of Academy of Finland. Keywords: Solid state detectors, X-ray detectors, Gamma detectors, Neutron detectors, Instrumentation for hadron therapy, Medical-image reconstruction methods and algorithms.

扫码加入交流群

加入微信交流群

微信交流群二维码

扫码加入学术交流群,获取更多资源